Rapid Determination of Urinary Total Porphyrins by Ion Exchange Chromatography

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Rapid determination of urinary total porphyrins by ion exchange chromatography.

Total urinary porphyrins were eluted from a commercially available anion exchange Chromatographie column with hydrochloric acid and determined spectrophotometrically. For 1 ml samples the optimum concentration range for measurement was found to lie between 0.1 and 1.5 mg of total porphyrin/1 urine. Assay of a single sample takes 12 min. The specificity (measurement at three wave lengths), sensi...

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Ion chromatography was used to determine urinary oxalate concentration. The minimal detectable limit in a standard solution was 0.02 flg/ml, and the regression line for the standard curve from 0.5 to 10 flg/ml had a significant correlation coefficient (p<O. 01), but it was difficult to obtain reproducible results with ion chromatography. There were two obstacles: Urine was always oversaturated ...

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ژورنال

عنوان ژورنال: Clinical Chemistry and Laboratory Medicine

سال: 1971

ISSN: 1434-6621,1437-4331

DOI: 10.1515/cclm.1971.9.5.415